Asteroid Confusions with Extremely Large Telescopes

Asteroids can be considered as sources of contamination of point sources and also sources of confusion noise, depending whether their presence is detected in the image or their flux is under the detection limit. We estimate that at low ecliptic latitudes, ~10,000--20,000 asteroids/sq. degree will be detected with an E-ELT like telescope, while by the end of Spitzer and Herschel missions, infrared space observatories will provide ~100,000 serendipitous asteroid detections. The detection and identification of asteroids is therefore an important step in survey astronomy.Comment: 8 pages, 4 figures, accepted by Earth, Moon and Planets, ELT Conference (Elba, 2009 Sept.) S

The Science of Sungrazers, Sunskirters, and Other Near-Sun Comets

This review addresses our current understanding of comets that venture close to the Sun, and are hence exposed to much more extreme conditions than comets that are typically studied from Earth. The extreme solar heating and plasma environments that these objects encounter change many aspects of their behaviour, thus yielding valuable information on both the comets themselves that complements other data we have on primitive solar system bodies, as well as on the near-solar environment which they traverse. We propose clear definitions for these comets: We use the term near-Sun comets to encompass all objects that pass sunward of the perihelion distance of planet Mercury (0.307 AU). Sunskirters are defined as objects that pass within 33 solar radii of the Sun’s centre, equal to half of Mercury’s perihelion distance, and the commonly-used phrase sungrazers to be objects that reach perihelion within 3.45 solar radii, i.e. the fluid Roche limit. Finally, comets with orbits that intersect the solar photosphere are termed sundivers. We summarize past studies of these objects, as well as the instruments and facilities used to study them, including space-based platforms that have led to a recent revolution in the quantity and quality of relevant observations. Relevant comet populations are described, including the Kreutz, Marsden, Kracht, and Meyer groups, near-Sun asteroids, and a brief discussion of their origins. The importance of light curves and the clues they provide on cometary composition are emphasized, together with what information has been gleaned about nucleus parameters, including the sizes and masses of objects and their families, and their tensile strengths. The physical processes occurring at these objects are considered in some detail, including the disruption of nuclei, sublimation, and ionisation, and we consider the mass, momentum, and energy loss of comets in the corona and those that venture to lower altitudes. The different components of comae and tails are described, including dust, neutral and ionised gases, their chemical reactions, and their contributions to the near-Sun environment. Comet-solar wind interactions are discussed, including the use of comets as probes of solar wind and coronal conditions in their vicinities. We address the relevance of work on comets near the Sun to similar objects orbiting other stars, and conclude with a discussion of future directions for the field and the planned ground- and space-based facilities that will allow us to address those science topics

Phase-curve analysis of comet 67P/Churyumov-Gerasimenko at small phase angles

Open Access article, published by EDP Sciences, under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Open Access funding provided by Max Planck Society.The Rosetta-OSIRIS images acquired at small phase angles in three wavelengths during the fly-by of the spacecraft on 9-10 April 2016 provided a unique opportunity to study the opposition effect on the surface of comet 67P/Churyumov-Gerasimenko (67P). Our goal is to study phase curves of the nucleus at small phase angles for a variety of surface structures to show the differences in their opposition effect and to determine which surface properties cause the differences.© N. Masoumzadeh et al. 2019OSIRIS was built by a consortium of the Max-Planck-Institut fur Sonnensystemforschung, Gottingen, Germany; the CISAS University of Padova, Italy; the Laboratoire d'Astrophysique de Marseille, France; the Instituto de Astrofisica de Andalucia, CSIC, Granada, Spain; the Research and Scientific Support Department of the ESA, Noordwijk, Netherlands; the Instituto Nacional de Tecnica Aeroespacial, Madrid, Spain; the Universidad Politechnica de Madrid, Spain; the Department of Physics and Astronomy of Uppsala University, Sweden; and the Institut fur Datentechnik und Kommunikationsnetze der Technischen Universitat Braunschweig, Germany. The support of the national funding agencies of Germany (DLR), France (CNES), Italy (ASI), Spain (MEC), Sweden (SNSB), and the ESA Technical Directorate is gratefully acknowledged. We thank the Rosetta Science Operations Centre and the Rosetta Mission Operations Centre for the successful rendezvous with comet 67P/Churyumov-Gerasimenko. This research has made use of the USGS Integrated Software for Imagers and Spectrometers (ISIS). We gratefully acknowledge the developers of SPICE and NAIF/PDS resources. This research has made use of the scientific software shapeViewer www.comet-toolbox.com.L.K.acknowledges a support from the NASA SSW grant 80NSSC17K0731

Surface evolution of the Anhur region on comet 67P/Churyumov-Gerasimenko from high-resolution OSIRIS images

Open Access article, published by EDP Sciences, under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.The southern hemisphere of comet 67P/Churyumov-Gerasimenko (67P) became observable by the Rosetta mission in March 2015, a few months before cometary southern vernal equinox. The Anhur region in the southern part of the comet's larger lobe was found to be highly eroded, enriched in volatiles, and highly active. Aims. We analyze high-resolution images of the Anhur region pre- and post-perihelion acquired by the OSIRIS imaging system on board the Rosetta mission. The Narrow Angle Camera is particularly useful for studying the evolution in Anhur in terms of morphological changes and color variations. Methods. Radiance factor images processed by the OSIRIS pipeline were coregistered, reprojected onto the 3D shape model of the comet, and corrected for the illumination conditions. Results. We find a number of morphological changes in the Anhur region that are related to formation of new scarps; removal of dust coatings; localized resurfacing in some areas, including boulders displacements; and vanishing structures, which implies localized mass loss that we estimate to be higher than 50 million kg. The strongest changes took place in and nearby the Anhur canyon-like structure, where significant dust cover was removed, an entire structure vanished, and many boulders were rearranged. All such changes are potentially associated with one of the most intense outbursts registered by Rosetta during its observations, which occurred one day before perihelion passage. Moreover, in the niche at the foot of a new observed scarp, we also see evidence of water ice exposure that persisted for at least six months. The abundance of water ice, evaluated from a linear mixing model, is relatively high (>20%). Our results confirm that the Anhur region is volatile-rich and probably is the area on 67P with the most pristine exposures near perihelion.© S. Fornasier et al. 2019OSIRIS was built by a consortium led by the Max-Planck-Institut fur Sonnensystemforschung, Goettingen, Germany, in collaboration with CISAS, University of Padova, Italy, the Laboratoire d'Astrophysique de Marseille, France, the Instituto de Astrofisica de Andalucia, CSIC, Granada, Spain, the Scientific Support Office of the European Space Agency, Noordwijk, The Netherlands, the Instituto Nacional de Tecnica Aeroespacial, Madrid, Spain, the Universidad Politechnica de Madrid, Spain, the Department of Physics and Astronomy of Uppsala University, Sweden, and the Institut fur Datentechnik und Kommunikationsnetze der Technischen Universitat Braunschweig, Germany. The support of the national funding agencies of Germany (DLR), France (CNES), Italy (ASI), Spain (MEC), Sweden (SNSB), and the ESA Technical Directorate is gratefully acknowledged. We thank the Rosetta Science Ground Segment at ESAC, the Rosetta Mission Operations Centre at ESOC and the Rosetta Project at ESTEC for their outstanding work enabling the science return of the Rosetta Mission. SF acknowledges the financial support from the France Agence Nationale de la Recherche (programme Classy, ANR-17-CE31-0004). The authors thank Dr. E. Howell for her comments and suggestions which helped us to improve this article

Regional unit definition for the nucleus of comet 67P/Churyumov-Gerasimenko on the SHAP7 model

Open Acces publication. This article is available under the Creative Commons CC-BY-NC-ND license and permits non-commercial use of the work as published, without adaptation or alteration provided the work is fully attributed.The previously defined regions on the nucleus of comet 67P/Churyumov-Gerasimenko have been mapped back onto the 3D SHAP7 model of the nucleus (Preusker et al., 2017). The resulting regional definition is therefore self-consistent with boundaries that are well defined in 3 dimensions. The facets belonging to each region are provided as supplementary material. The shape model has then been used to assess inhomogeneity of nucleus surface morphology within individual regions. Several regions show diverse morphology. We propose sub-division of these regions into clearly identifiable units (sub-regions) and a comprehensive table is provided. The surface areas of each sub-region have been computed and statistics based on grouping of unit types are provided. The roughness of each region is also provided in a quantitative manner using a technique derived from computer graphics applications. The quantitative method supports the sub-region definition by showing that differences between sub-regions can be numerically justified.© 2018 The AuthorsThe team from the University of Bern is supported through the Swiss National Science Foundation and through the NCCR PlanetS. The project has also received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 686709. This work was supported by the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number 16.0008-2

Models of Rosetta/OSIRIS 67P Dust Coma Phase Function

The phase function of the dust coma of comet 67P has been determined from Rosetta/OSIRIS images. This function shows a deep minimum at phase angles near 100°, and a strong backscattering enhancement. These two properties cannot be reproduced by regular models of cometary dust, most of them based on wavelength-sized and randomly oriented aggregate particles. We show, however, that an ensemble of oriented elongated particles of a wide variety of aspect ratios, with radii r 10 μm, and whose long axes are perpendicular to the direction of the solar radiation, are capable of reproducing the observed phase function. These particles must be absorbing, with an imaginary part of the refractive index of about 0.1 to match the expected geometric albedo, and with porosity in the 60%-70% range.© 2018. The American Astronomical Society. All rights reserved..OSIRIS was built by a consortium of the Max-Planck-Institut fur Sonnensystemforschung, in Gottingen, Germany, CISAS-University of Padova, Italy, the Laboratoire dAstrophysique de Marseille, France, the Instituto de Astrofisica de Andalucia, CSIC, Granada, Spain, the Research and Scientific Support Department of the European Space Agency, Noordwijk, The Netherlands, the Instituto Nacional de Tecnica Aeroespacial, Madrid, Spain, the Universidad Politecnica de Madrid, Spain, the Department of Physics and Astronomy of Uppsala University, Sweden, and the Institut fur Datentechnik und Kommunikationsnetze der Technischen Universitat Braunschweig, Germany. The support of the national funding agencies of Germany (DLR), France (CNES), Italy (ASI), Spain (MEC), Sweden (SNSB; grant No. 74/10: 2), and the ESA Technical Directorate is gratefully acknowledged. H.R. was also supported by grant No. 2011/01/B/ST9/05442 of the Polish National Science Center. We thank the ESA teams at ESAC, ESOC, and ESTEC for their work in support of the Rosetta mission We thank the Rosetta Science Ground Segment at ESAC, the Rosetta Mission Operations Centre at ESOC, and the Rosetta Project at ESTEC for their outstanding work enabling the science return of the Rosetta Mission. This work was supported by contracts AYA2015-67152-R and AYA2015-71975-REDT from the Spanish Ministerio de Economia y Competitividad

Durable response with single-agent acalabrutinib in patients with relapsed or refractory mantle cell lymphoma

Bruton tyrosine kinase (BTK) inhibitors have greatly improved the spectrum of treatment options in mantle cell lymphoma (MCL) [1–4]. Acalabrutinib is a highly selective, orally administered, and potent BTK inhibitor with limited off-target activity [5]. Acalabrutinib was approved in 2017 by the US Food and Drug Administration for the treatment of relapsed/refractory MCL based on clinical data from the open-label, multicenter, phase 2 ACE-LY-004 study of acalabrutinib 100 mg twice daily [1]. Here, we present updated results from the ACE-LY-004 study after a median 26-month follow-up. Eligibility criteria and study design were published previously (Supplementary methods) [1]. Analysis of minimal residual disease (MRD) was conducted after complete response (CR) or partial response (PR) was achieved using the quantitative ClonoSEQ next-generation sequencing (5 × 10−6 ) assay (Adpative Biotechnologies, Seattle, WA, USA) in consenting patients with available paired archival tumor and whole blood samples. Data are updated as of February 12, 2018

Regional unit definition for the nucleus of comet 67P/Churyumov-Gerasimenko on the SHAP7 model

The previously defined regions on the nucleus of comet 67P/Churyumov-Gerasimenko have been mapped back onto the 3D SHAP7 model of the nucleus (Preusker et al., 2017). The resulting regional definition is therefore self-consistent with boundaries that are well defined in 3 dimensions. The facets belonging to each region are provided as supplementary material. The shape model has then been used to assess inhomogeneity of nucleus surface morphology within individual regions. Several regions show diverse morphology. We propose sub-division of these regions into clearly identifiable units (sub-regions) and a comprehensive table is provided. The surface areas of each sub-region have been computed and statistics based on grouping of unit types are provided. The roughness of each region is also provided in a quantitative manner using a technique derived from computer graphics applications. The quantitative method supports the sub-region definition by showing that differences between sub-regions can be numerically justified